I-Cycobalamin yenye ye-vitamin B complexes, ene-anti-pernicious anemia effect. Ligama elinikwe yikristale ye-vitamin B12, into eyimfuneko ekuphuhliseni iibhaktheriya kunye nezilwanyana. Ngaphandle kwe-C, H, O, N, P kunye ne-Co, i-ad-ribose conjugate ye-5,6-dimethe-rbenzimidazole yinxalenye yesakhiwo sayo. AR Todd et al. beka phambili ifomyula yesakhiwo, ebizwa ngokuba yi-cyanocobalamin kuba i-cyano ilungelelaniswa kwi-cobalt. Ubuninzi bokufunxa kwisisombululo samanzi yi-278,361,548 nm. Ngo-1948, u-E.L.Rickes wase-United States kunye no-E. Ukususela ngoko, le nto ifunyenwe kwi-actinomycete ethile (StrePtomyces griseum).I-Cyanocobalamin ikwayinto yokukhula kweehagu namantshontsho, kwaye ikwayinto enye neprotheyini yezilwanyana eyimfuneko ekuqanduselelweni kwamaqanda. I-Vitamin B12, enikwe izigulane ezinezifo ezinobungozi kwi-microgram ye-150, inokunyusa iiseli ezibomvu zegazi malunga namaxesha angama-2, kunye ne-3-6 micrograms inokuvelisa imiphumo. Kwi-vivo, ihanjiswa egazini ngendlela yokudibanisa ne-trans-cobalamin protein (iprotein ye-globular), kwaye ikhona ngendlela ye-coenzyme kwiithishu ezahlukeneyo. Kunye ne-folic acid, ibandakanyeka kwimetabolism yokudluliselwa kwe-methyl kunye ne-methyl esebenzayo yokuvelisa. Kwaye ube yinto ebalulekileyo ye-purine, i-pyrimidine kunye nezinye i-biosynthesis.
