I-Niclosamide, i-CAS 50-65-7

Ingcaciso yeMveliso

I-Molluscicide
Inombolo yePD: 50-65-7
Inombolo yeCAS: 50-65-7
Amanye Amagama:
igama:I-Niclosamide
MF:C13H8Cl2N2O4
I-EINECS No.: 200-056-8
Ilizwe:Umgubo
Ubunyulu:99%
Isicelo:Isibulali-inkumba, i-molluscicide
Inombolo yoMfanekiso:HHWX-50-65-7
Umbala:Umgubo weCrystalline omhlophe okanye okhanyayo
Ubunzima beMolekyuli:327.12
Isampulu:Iyafumaneka
Isivavanyi:99.0 % min
Indawo yokunyibilika: 225-230 °
ubushushu bokugcina:0-6°C
Isicelo:Niclosamide CAS 50-65-7, Unyango lwezilwanyana

Isiphumo seMveliso

Imichiza yokutshabalalisa ukhula ekhethiweyo. Ukulawulwa kwengca yonyaka (Echinochloa, Digitaria, Setaria, Brachiaria, Panicum, kunye neCyperus) kunye nokhula olunamagqabi abanzi (Amaranthus, Capsella, Portulaca) kumbona, amazimba, iswekile, iimbotyi zesoya, amandongomane, umqhaphu, iswekile beet, ifolishi. beet, iitapile, imifuno eyahlukahlukeneyo, oojongilanga, kunye nezityalo ze-pulse. Isoloko isetyenziswa ngokudityaniswa nemichiza yokutshabalalisa ukhula enamagqabi abanzi, yandisa uluhlu lomsebenzi. 

Iimpawu ezisisiseko

Inombolo yeCAS:50-65-7

Ifomula yemolekyuli :I-C13H8Cl2N2O4

Ubunzima beMolekyuli:327.12

Ubunzima obuchanekileyo:325.986115

PSA:95.2 A^2

LogP:10 @ pH 9.6

EINECS :200-056-8

InChIKeys :RJMUSRYZPJIFPJ-UHFFFAOYSA-N

I-H-bond Accepter:4

I-H-bond Donor:2

RBN:2

Iimpawu

Ubuninzi: 1.6±0.1 g/cm3

Indawo yokunyibilika :225-230 °

Indawo yeBolling: 424.5±45.0 °C kwi-760 mmHg

Indawo yokuflasha :210.5±28.7 °C

Refractive Index :1.709

Ukunyibilika :iacetone: imethanol: inyibilika 50mg/mL (methanol:acetone (1:1))

Imeko yoGcino :0-6°C

Uxinzelelo lomphunga:<9.87X10-9 mm Hg ku-20 deg C

Uzinzo :Izinzile ukutshisa kwaye i-hydrolysed nge-asidi edibeneyo okanye i-alkali.

Ulwazi ngoKhuseleko

Ikhowudi yeHS: 2924299090

Inombolo ye-UN:UN 3077 9/PG 3

WGK_Germany :2

Ikhowudi yomngcipheko:50

Imiyalelo yoKhuseleko :29

Inombolo ye-RTECS.VN8400000

Ugcino :Indawo yokugcina impahla ingena umoya, ubushushu obuphantsi kwaye yomile; igcinwe kwaye ithuthwe ngokwahlukeneyo kwizinto zokutya

Ikhowudi ye-P:P273

Iingxelo zobungozi:H400

Ukutsha :Ukutsha kuvelisa ityhefu yekloridi kunye neegesi zenitrogen oxide

Ubutyhefu :I-Oral-Rat LD50: 2500 mg / kg; I-Oral-Mouse LD50: 1000 mg / kg

Iklasi Yetyhefu:ngokuphakathi

Ukusetyenziswa kweMveliso

I-inhibitor ye-Stat3 signing pathway kunye ne-FRAP inhibitor.Ludidi olutsha lweyeza lokubulala intshulube elinokuthi lisetyenziswe ukugxotha intshulube kwizilwanyana ezifana neehagu kunye neenkomo. Isenokubulala iinkumba. Isenokusetyenziswa njengeyeza lokunqanda iintshulube, kwaye isenokusetyenziswa ukuthintela nokulawula inkumba

Iindlela zeMveliso

Izixa ezilinganayo ze-2-chloro-4-nitroaniline kunye ne-5-chlorosalicylic acid zinyibilika kwi-xylene (okanye i-chlorobenzene), ifudunyezwe ukubilisa, emva koko i-phosphorus trichloride (okanye i-phosphorus oxychloride) yongezwa kancinci, kwaye iqhubekile i-Reflux 3h. Emva kokupholisa, iikristale ziyahluzwa ukuze zibe yimveliso.

Izinto eziphathekayo kunye neeMveliso

Material:I-Phosphorus oxychloride, i-2-Chloro-4-nitroaniline